Is a pharmacy profitable? Calculate margins and break-even sales
Understand gross margin, markup, operating profit and cash, with worked examples you can replace with your own pharmacy’s numbers.
By the RunMyPharmacy team · Updated · 5 min read

Start with your own numbers, not a promised profit rate
A pharmacy’s result depends on its product mix, buying terms, rent, payroll, expiry losses and other costs. There is no single profit percentage this guide can promise. Separate turnover from money available to the owner.
Use a consistent accounting period and a consistent treatment of taxes, returns and discounts. Ask your accountant how your actual records should treat these items. The following figures are hypothetical teaching examples, not Pakistani market averages.
Gross margin is different from markup
Assume monthly net sales of Rs 1,000,000 and cost of goods sold of Rs 800,000. Gross profit is Rs 200,000. Gross margin is 200,000 ÷ 1,000,000 = 20%. Markup is 200,000 ÷ 800,000 = 25%. Both calculations describe the same example, but they answer different questions.
Cost of goods sold reflects the stock sold during the period; it is not simply that month’s supplier payments. Buying a large amount of unsold inventory affects cash without making all of that stock a current sales expense.
Find contribution before calculating break-even
Suppose the same hypothetical store has Rs 30,000 of costs that vary with these sales, such as applicable payment processing and delivery costs. Contribution is Rs 200,000 − Rs 30,000 = Rs 170,000, or 17% of sales.
With Rs 150,000 of fixed monthly operating costs, the illustrated operating surplus is Rs 20,000 before any additional charges not included in the model. Define owner remuneration, finance costs, taxes and stock losses explicitly; otherwise a small apparent profit can disappear when omitted expenses are added.
Turn break-even into a daily target
For a stable product mix, approximate break-even sales equal fixed costs divided by the contribution margin ratio. With the example above: Rs 150,000 ÷ 0.17 ≈ Rs 882,353 per month. Over 30 trading days that is approximately Rs 29,412 a day.
If the illustrative average bill is Rs 800, the target is about 37 bills a day. This is a planning estimate, not a sales forecast. Changing the product mix, discounts or delivery costs changes contribution. If contribution is zero or negative, this formula cannot produce a workable positive break-even target.
Test a less favourable margin before signing a lease
| Assumed contribution ratio | Fixed monthly costs | Approximate monthly break-even sales |
|---|---|---|
| 12% | Rs 150,000 | Rs 1,250,000 |
| 15% | Rs 150,000 | Rs 1,000,000 |
| 18% | Rs 150,000 | Rs 833,333 |
Compare each target with observed footfall and realistic transactions. A location with expensive rent needs evidence of extra contribution, not just a busy road. Repeat the model with fewer trading days or a lower average bill to understand how much headroom you have.
Measure the cost of a discount
For a hypothetical item sold at Rs 1,000 with cost of Rs 800, gross profit is Rs 200. Reducing the selling price to Rs 950 leaves Rs 150 before other costs. A 5% price discount reduced gross profit by 25%.
A promotion may still make sense in a properly evaluated context, but it needs enough additional contribution to cover the reduction. Do not assume more turnover automatically produces more profit. Follow applicable pricing and promotional rules and avoid incentives that encourage inappropriate medicine purchases.
Why profit and cash can disagree
Cash moves when you collect money, buy inventory, settle supplier invoices, pay rent or withdraw funds. Accounting profit follows the recognition of sales and their associated costs. Credit purchases can temporarily improve the bank balance while creating a bill due later.
Build a rolling cash forecast with actual due dates. Include opening-stock payments, supplier balances, approved credits, payroll, owner withdrawals and the reserve you need to operate. Keep unaccepted return claims out of available cash.
Review seven numbers each month
- Net sales after recorded returns and discounts.
- Cost of goods sold using a consistent stock method.
- Gross profit and contribution ratio.
- Fixed operating costs including agreed owner remuneration.
- Expiry, damage and unexplained stock losses.
- Cash available and supplier amounts due.
- Break-even target compared with actual trading days and bills.
Download the break-even worksheet
Investigate changes before reacting with blanket price cuts. A lower contribution ratio may come from product mix, purchase cost, missing discounts, returns or a recording error.
Frequently asked questions
What profit margin should I expect?
Estimate it from verified buying terms, realistic selling prices and your product mix. A single advertised percentage cannot represent every pharmacy or its operating expenses.
Is supplier discount my profit?
It affects purchase cost, but selling discounts, cost of goods sold and operating expenses still matter. A supplier’s discount percentage is not your net profit percentage.
Can I take out all the monthly profit?
Check cash, supplier due dates, taxes, future purchases and your operating reserve first. Profit shown in a report may not be cash available to withdraw.
Official sources
Try RunMyPharmacy free
Pharmacy software for Pakistan, free during early access. No credit card required.
Create your free accountRelated
How much does it cost to open a pharmacy in Pakistan? Build your startup budget
Build a pharmacy startup budget from local quotations, with a worked PKR example, operating-reserve calculation and costs that owners often miss.
Where should you open a pharmacy? A practical location checklist
Compare residential areas, clinic clusters and busy roads using customer access, competition, premises suitability and a rent-versus-sales test.
Reducing Expired Stock
Why pharmacies lose money to expired stock and how to stop it: batch tracking, FEFO, tiered expiry alerts, smarter reordering and supplier returns.